`r lifecycle::badge("deprecated")`
This function is deprecated - improved modeling functions can be found in
the package "ChAI" at https://github.com/aifimmunology/ChAI
pilotLMEM
Runs linear mixed-effects modeling for
continuous, non-zero inflated data using lmer
Arguments
- ExperimentObj
A SummarizedExperiment-type object generated from chromVAR, makePseudobulkRNA, or other. Objects from getSampleTileMatrix can work, but we recommend runZIGLMM for those objects, not runLMEM>
- assayName
a character string, matching the name of an assay within the SummarizedExperiment. The assay named will be used for modeling.
- modelFormula
The formula to use with lmerTest::lmer, in the format (exp ~ factors). All factors must be found in column names of the ExperimentObj metadata.
- pilotIndices
A vector of integers defining the subset of the ExperimentObj matrix. Default is 1:10.
- verbose
Set TRUE to display additional messages. Default is FALSE.